Los Angeles Dodgers pitcher Yoshinobu Yamamoto just threw 68 pitches across five dominant innings in his last Spring Training start last Friday. That means Yamamoto should be on track to throw around 80 pitches in his first regular season start.

All the Dodgers pitcher has to do is pitch into the sixth inning, and WalterPicks believes that will be the case. Our projection model predicts Yamamoto to record 16.4 outs on Thursday. He will also face a Diamondbacks team that he dominated last year, allowing only six earned runs across 25 innings pitched (2.16 ERA).

This prop has a 6.3% Value on Underdog.

Michael Busch is fresh off a breakthrough campaign in 2025. However, this line might be too high on Opening Day. This game is expected to feature crazy winds blowing in from left field, making runs hard to come by.

Although Busch has never faced Nationals starter Cade Cavalli, Walter only projects the Cubs first baseman to finish with 1.9 hits + runs + RBI in this contest. Expect this to be a lower-scoring game, with most sportsbooks setting the over/under at 7.5 runs scored.

This prop has a 17.2% Value on DraftKings.

Yordan Alvarez had an injury-riddled 2025 season, playing in only 48 games for the Houston Astros. Alvarez, though, will enter the 2026 campaign fully healthy. He is now in a prime spot to do some damage against Angels starter Jose Soriano.

Alvarez is 1-for-3 lifetime against Soriano and has the potential to tally at least one RBI in this contest. The Astros slugger batted over .315 with over 20 home runs against fastball-type pitches in his last full season in 2024. Soriano’s fastball had poor metrics in 2025, as opposing hitters batted .290 with 19 extra-base hits.

This prop has a 6.2% Value on Bet MGM.

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